INTRODUCTION TO THE CELL

CELL
-          This most basic and living unit of any organism.
-           Cell organelles perform various functions in the cell, as organs and organ systems do in our body.













CELL MEMBRANE
 -  Cell membranes are semi permeable.
-   These membranes are composed of proteins and phospholipids.
-    FUNCTIONS
                                1- Separates cell organelles from external environment.
                                2- Control the exchange of gases and solutes.
                                3- At times functions as a site for photosynthesis and etc.
4- It carries receptors to which various hormones,   antibiotics and other chemicals may attach   and invite a variety of reaction



 MEMBRANE PROTEINS
-  Different types of proteins occur in different membranes.
- Usually hydrophobic portions of the proteins interact with lipids while hydrophilic aqueous contents of the membrane.
- Other membrane proteins may function as receptors for ligands, electrons carrier.
- Some membrane proteins are glycosylated for cell to cell adhesions.
- They play important rule in the immune response.
-  The structure of a membrane can be explained with a fluid mosaic model.


NUCLEUS
- It is found in all eukaryotic cells.
- It is largest of all cell organelles.
- Nuclear membrane contains pores to allow exchange of substances between nucleus and cytoplasm.
-  Nucleus contains one or more nucleoli, chromatin and gel like nucleoplasm.
- Chromatin is composed of DNA which is compliced with basic proteins called histons.
- DNA and histons are organised into bead like structure called NUCLEOSOMES.
-The loosely coiled chromatins that stain less are called euchromatin and the tightly coiled are called   heterochromatin
















CYTOPLASM
-          This is the aqueous substance inside the cell.
-          The solute part of cytoplasm is called cytosol.
-          Cytosol is 90% of water in which ions, salts, sugars, amino acids, fatty acids, nucleotides and gases are dissolved.
-          The nucleus and cytoplasm constitute the protoplasm.
-          Cytoplasm is also the site of many other metabolic pathways.




 ENDOPLASMIC RETICULUM ( ER )
-          It is complex network of membranes running through the cytoplasm of the eukaryotic cells.
-          It consists of flattened membranes called CISTERNAE.

TYPES:-
1.       Rough endoplasmic reticulum (RER)

§  It has ribosomes embedded on the surface of cisternae , making it look rough.
§  It helps in protein synthesis.
§  ER sacs covered with ribosomes are called microsomes.


2.       Smooth endoplasmic reticulum (SER)
§  It does not have ribosomes embedded on it.
§  This helps in lipid synthesis.
§  It is also the site of glycosylation.

RIBOSOMES
-          This is found in plant animal and bacterial cells.
-          Found throughout the cytoplasm in large numbers.
-          This is the site of protein synthesis.
-          Each ribosome consists of two subunits a smaller unit and a larger unit.
-          It consists of equal amount of RNA and protein.
-          RNA found here is called ribosomal RNA (rRNA).


-          TYPES:-
      
1.       70S

§  This type is found only in prokaryotes.
§  It has two subunits 50S and 30S.
§  S stands for Svedberg (unit of sedimentation rate).

2.       80S
§  Found only in eukaryotic cells.
§  The two subunits are 60S and 40S.



GOLGI APPARATUS
-          Found in all eukaryotes.
-          Consists of flattened membrane bound sacs called cisterane.
-          Cisterane is formed by the fusion of vesicles, which bud off from the ER.
-          Site of glycosylation.
-          It synthesizes lysosomes.
-          Packing and moving of organelles in and out if the cell.




LYSOSOMES
                              - These are single membrane organelles.
                            -  Contains hydrolytic enzymes like protease, nuclease and lipase.




MITOCHONDRIA
-          These are elongated organelles bounded by two membranes,
-          Inner membrane is folded and called cristae.
-          Its matrix contains few ribosomes, DNA and phosphate granules.
-          Its matrix site for kerbs cycle.
-          Its site for respiration and ATP synthesis.
-          Cristae is the site for oxidative phosphorylation.
-          It is known as power house of the cell.




PLASTIDS
-          These are found only in plant cells and bounded by two membranes.
-          Types
1)       Chloroplast   - contains chlorophyll and green in clour and carries out photosynthesis.

2)       Chromopast – these are non photosynthetic colored plastids containing red, orange and yellow pigments.

3)       Leucoplasts  -  Colorless plastids and lack pigments. These are modified into food storage sites.

 CYTOSKELETON
     
       -These are fibrous protein structure which exsists in all eukaryatic cells giving them their shape.
                   -Types
1)       Microtubules
-   Un-branched, hollow cylindrical organelles and consists of protein called tubulin.
-  These are responsible for the movement of chromosomes and other organelles such as golgi vesicle.

2)    Micro filaments
-  These are fine protein filaments.
- Made of actin.
- Occur in sheets or bundles just below the all membrane.
                                                        - Involved in endocytosis and exocytosis.

               


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